- Clb5 Clb6 Mutants
- clb5∆ clb6∆
- TAB6-1 clb5∆ clb6∆
- cdc20∆ clb5∆
- cdc20∆ pds1∆ clb5∆
- CLB2-db∆ clb5∆
- CLB2-db∆ clb5∆ in galactose
- cln1∆ cln2∆ clb5∆ clb6∆
- CLB5-db∆
- CLB5-db∆ sic1∆
- CLB5-db∆ pds1∆
- CLB5-db∆ pds1∆ cdc20∆
- GAL-CLB5
- GAL-CLB5 cdh1∆
- GAL-CLB5 sic1∆
- GAL-CLB5-db∆
- cln1∆ cln2∆ cln3∆ multi-copy CLB5
- cln1∆ cln2∆ cln3∆ GAL-CLB5
GAL-CLB5 sic1∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksb5'=0.012, ksc1'=ksc1"=0, MDT=150.
Arrest: It dies after the first cycle, Ori not relicensed.
Experiments:
Jacobson, M.D., Gray, S., Yuste-Rojas, M. and Cross, F.R. (2000). Testing cyclin specificity in the exit from mitosis. Mol. Cell. Biol. 20:4483-4493.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Lethal, data not shown.
Comments: It can exit the first mitosis but [ORI] (grey line) is not relicensed, due to high Clb5 kinase activity in G1.